Will I flunk a drug test if I medicate with CBD-rich cannabis? Drug tests are geared toward identifying THC, not CBD or another cannabinoid. If one medicates with CBD-rich cannabis that has only a small amount of THC, the THC may register on a drug test. A drug test geared toward CBD would not be an effective law enforcement tool, given that CBD is not psychoactive and does not cause impairment.

How is CBD metabolized when consumed orally? Is it converted to another compound? CBD is metabolized into an analogous compound, 7-hydroxy-CBD. There may also be some 6-OH-CBD. But scientists know relatively little about the activity (or lack thereof) of these compounds.

Does CBD interact with other medications? Yes. CBD inhibits the cytochrome P450 enzyme, which is involved in metabolizing many drugs. Compounds in grapefruit inhibit the same enzyme group, which is why physicians advice patients not to eat grapefruit shortly before or after taking a medication. By inhibiting cytochrome P450, CBD can either reduce or increase the effects of other drugs. In some situations, it may be advisable for a physician to monitor a patient’s blood levels of other medications while taking CBD.

What do you mean when you say a cannabis strain or product is “CBD-rich” or "CBD dominant?" 

By “CBD-rich,” we mean a cannabis strain or product that has equal amounts of CBD and THC, or more CBD than THC (usually at least 4 percent CBD by dry weight.). By “CBD-dominant,” we mean strains or products that are CBD-rich but have very little THC content.